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Chronic cough in patients with sleep-disordered breathing
1Dept of Respiratory Medicine, King's College Hospital, London, SE5 9RS, UK.
Chronic cough affects one-third of patients with sleep-disordered breathing (SDB). This cough is linked to female sex, heartburn, and rhinitis, impacting quality of life.
Area of Science:
- Sleep Medicine
- Respiratory Medicine
- Cough Medicine
Background:
- Chronic cough can be the primary symptom of obstructive sleep apnea.
- Sleep-disordered breathing (SDB) affects a significant portion of the population.
- Understanding cough in SDB is crucial for patient management.
Purpose of the Study:
- To determine the prevalence of chronic cough in SDB patients.
- To assess the severity and quality of life impact of chronic cough in SDB.
- To identify factors associated with chronic cough in SDB.
Main Methods:
- 108 consecutive SDB patients completed questionnaires on sleep and respiratory health.
- Validated tools included the Leicester Cough Questionnaire (LCQ) and Epworth Sleepiness Scale (ESS).
- Chronic cough was defined as lasting longer than 2 months.
Main Results:
- 33% of SDB patients reported chronic cough, significantly impacting their quality of life (LCQ score 17.7).
- Chronic cough was more prevalent in females (61%) compared to males (17%).
- Associated factors included nocturnal heartburn (28%) and rhinitis (44%).
Conclusions:
- Chronic cough is common in SDB patients and associated with female sex, heartburn, and rhinitis.
- Continuous positive airway pressure (CPAP) therapy's effect on cough in SDB warrants further investigation.
- Identifying these associations can improve SDB patient care and treatment strategies.
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