Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Peptic Ulcer Disease IV: Management01:26

Peptic Ulcer Disease IV: Management

Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current medication...
Peptic Ulcer Disease V: Surgical Management and Nursing Care01:25

Peptic Ulcer Disease V: Surgical Management and Nursing Care

Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Peptic Ulcer Disease III: Clinical Manifestations and Complications01:25

Peptic Ulcer Disease III: Clinical Manifestations and Complications

Duodenal UlcersDuodenal ulcers are the most common form of peptic ulcer disease, presenting with chronic, intermittent epigastric pain. Pain typically appears 2–3 hours after meals, especially when the stomach is empty, often waking patients at night. It is characteristically relieved by food or antacids (“pain–food–relief”). Some patients remain asymptomatic until complications like bleeding or perforation emerge, particularly with NSAID or anticoagulant use.Gastric UlcersGastric ulcers share...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical outcomes of one-step EUS-guided hepaticogastrostomy using an 8F stent introducer featuring an ultra-tapered metal tip and a preloaded partially covered metal stent (with video).

Endoscopic ultrasound·2026
Same author

Comparative Effectiveness of Peroral Endoscopic Myotomy, Laparoscopic Heller Myotomy, Pneumatic Dilation, and Botulinum Toxin for Achalasia: A Network Meta-Analysis.

Journal of clinical gastroenterology·2026
Same author

The Use of Endoscope Tip Protectors: Results of a Prospective, Blinded Operational Quality Improvement Analysis.

Digestive diseases and sciences·2026
Same author

Comparison of 4 first-line endoscopic biliary drainage modalities in distal malignant biliary obstruction: A systematic review and network meta-analysis.

Endoscopic ultrasound·2026
Same author

Self-expandable metal stents versus plastic stents for unresectable malignant hilar biliary obstruction: A systematic review and meta-analysis of reconstructed individual patient data from randomized controlled trials with meta-regression.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2026
Same author

Adenoma and Sessile Serrated Polyp Detection Rates in Adults Using Glucagon-Like Peptide-1 Receptor Agonists.

Clinical and translational gastroenterology·2025

Related Experiment Videos

Managing acute upper GI bleeding, preventing recurrences.

Mazen Albeldawi1, Mohammed A Qadeer, John J Vargo

  • 1Department of Internal Medicine, Cleveland Clinic, OH 44195, USA.

Cleveland Clinic Journal of Medicine
|February 4, 2010
PubMed
Summary

Acute upper gastrointestinal bleeding requires prompt assessment and endoscopic intervention. Patients with bleeding ulcers benefit from proton pump inhibitors, with treatment tailored to endoscopic findings and clinical status.

Related Experiment Videos

Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Emergency Medicine

Background:

  • Acute upper gastrointestinal (GI) bleeding is a frequent and serious medical condition.
  • Prompt evaluation and management are crucial for patient outcomes.

Purpose of the Study:

  • To outline the diagnostic and therapeutic approach for acute upper GI bleeding.
  • To emphasize the role of endoscopy and proton pump inhibitors.

Main Methods:

  • Endoscopic examination for diagnosis, assessment, and potential treatment of upper GI lesions.
  • Administration of proton pump inhibitors for patients with bleeding ulcers.

Main Results:

  • Endoscopy effectively diagnoses and can treat various upper GI bleeding sources.
  • Proton pump inhibitor therapy is indicated for bleeding ulcers, guided by clinical and endoscopic data.

Conclusions:

  • A systematic approach involving endoscopy and targeted medical therapy, such as proton pump inhibitors, is essential for managing acute upper GI bleeding.