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Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
3f prosthesis aortic cusp replacement: implantation technique and early results
Ravi Pillai1, Chandana Ratnatunga, Jia Lin Soon
1Department of Cardiothoracic Surgery, John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9DU, UK. ravi.pillai@nds.ox.ac.uk
Asian Cardiovascular & Thoracic Annals
|February 4, 2010
Summary
The 3f bioprosthesis, a novel equine pericardial stentless valve, shows promising early results in aortic valve replacement. This unique valve design preserves native aortic sinuses, with favorable hemodynamics and low complication rates observed in initial patient follow-ups.
Area of Science:
- Cardiovascular Surgery
- Biomaterials Science
- Medical Devices
Background:
- Stentless aortic bioprostheses have a decade-long history of successful clinical use.
- The 3f bioprosthesis represents a new option, utilizing equine pericardium in a unique tubular design.
- This design aims to preserve native aortic sinuses after implantation.
Purpose of the Study:
- To evaluate the early clinical outcomes and hemodynamic performance of the 3f bioprosthesis.
- To assess the feasibility and safety of implanting this novel stentless aortic valve.
- To determine the accuracy of pre-operative echocardiographic sizing for prosthesis selection.
Main Methods:
- Prospective assessment of 46 consecutive patients undergoing aortic valve replacement with the 3f bioprosthesis.
- Echocardiography performed at 6 months, 12 months, and annually post-implantation.
- Median follow-up duration of 2.1 years.
Main Results:
- One early and four late deaths occurred, none attributed to the valve.
- The 2-year mean transvalvular gradient was 8.8 mm Hg.
- Mean echocardiographic aortic regurgitation was grade 0.4, indicating trivial leakage. Pre-operative sizing accurately predicted prosthesis size.
Conclusions:
- The 3f bioprosthesis is technically easy to implant and demonstrates favorable early clinical results.
- Hemodynamic profiles are consistent with other established stentless prostheses.
- Longer-term follow-up is necessary to ascertain the durability of the 3f bioprosthesis.