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Updated: Jun 16, 2026

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Published on: March 7, 2025

The pre-diabetic epidemiological study in Depok, West Java.

Em Yunir¹, Sarwono Waspadji, Ekowati Rahajeng

¹Department of Internal Medicine, University of Indonesia, Jakarta Pusat, Republic of Indonesia. dr_yunir@yahoo.com

Acta Medica Indonesiana

|February 4, 2010

Summary

This summary is machine-generated.

This study found that 4.13% of adults in Depok have impaired fasting glucose (IFG) and 24.25% have impaired glucose tolerance (IGT). Overall, 33.96% of the population exhibits pre-diabetic conditions.

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Last Updated: Jun 16, 2026

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Published on: March 7, 2025

Area of Science:

Endocrinology
Public Health
Epidemiology

Background:

Pre-diabetes, characterized by impaired fasting glucose (IFG) and impaired glucose tolerance (IGT), is a growing public health concern.
Early identification and management of pre-diabetes are crucial for preventing progression to type 2 diabetes.

Purpose of the Study:

To determine the prevalence of IFG and IGT in the general adult population of Depok Area, West Java.
To assess the combined prevalence of IFG and IGT, indicating a pre-diabetic state.

Main Methods:

A two-stage random sampling method was employed in Depok Area, West Java, targeting individuals aged 25 years and above.
Data collection followed the WHO Step Wise Approach, defining pre-diabetes based on ADA 2003 criteria for IFG (fasting blood glucose 100-125 mg/dL) and IGT (2-hour glucose load 140-199 mg/dL).

Main Results:

Out of 969 eligible participants, 4.13% had isolated IFG, and 24.25% had isolated IGT.
A significant 5.68% of participants presented with mixed IFG and IGT.
The overall prevalence of pre-diabetes was found to be 33.96% in the study population.

Conclusions:

The study highlights a substantial prevalence of pre-diabetes in the Depok Area, with isolated IGT being more common than isolated IFG.
A considerable proportion of the population exhibits combined IFG and IGT, underscoring the need for targeted public health interventions.
These findings emphasize the importance of screening and early management strategies for pre-diabetes in this region.