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Updated: Jun 16, 2026

A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images
Published on: April 21, 2023
Low false-negative rate of cytology in thyroid nodules >or= 4 cm
Pedro Weslley Rosario1, Daniela Santos Salles, Breno Bessa
1Programa de Pós-graduação, Santa Casa de Belo Horizonte, Belo Horizonte, MG, Brasil. pedrorosario@globo.com
Objective:
To report the results of cytology and histology obtained for a series of systematically resected thyroid nodules >or= 4 cm.
Methods:
A group of 151 patients with thyroid nodules >or= 4 cm was submitted to surgery despite the cytology result.
Results:
Malignancy was confirmed histologically in 22.5% of the patients. Excluding cases of insufficient material, cytology was benign in only 3/31 carcinomas (90.3% sensitivity). The frequency of malignancy was 35% among nodules with indeterminate cytology (follicular neoplasm), and there was a predominance (77%) of papillary carcinoma. The negative predictive value of benign cytology was 96.4%.
Conclusions:
The false-negative rate of cytology in thyroid nodules >or= 4 cm does not justify systematic resection of these nodules in asymptomatic patients with benign cytology.
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