Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Intestinal Obstruction I: Introduction01:29

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Trimethylamine-N-oxide is elevated in the acute phase after ischaemic stroke and decreases within the first days.

European journal of neurology·2020
Same author

["Hand, foot, eye?"]

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2019
Same author

[New possibilities with retroflexed functional endoscopy].

HNO·2018
Same author

Esophageal dysfunction in different stages of Parkinson's disease.

Neurogastroenterology and motility·2016
Same author

Update S3-guideline: "sedation for gastrointestinal endoscopy" 2014 (AWMF-register-no. 021/014).

Zeitschrift fur Gastroenterologie·2016
Same author

[S3-guidelines "sedation in gastrointestinal endoscopy" 2014 (AWMF register no. 021/014)].

Zeitschrift fur Gastroenterologie·2015
Same journal

[Version 7.0 of the S3 Guideline on Ulcerative Colitis sets out clearly defined treatment goals, an open treatment sequence, and a call for improved cross-sectoral care].

Zeitschrift fur Gastroenterologie·2026
Same journal

Zeitschrift fur Gastroenterologie·2026
Same journal

Zeitschrift fur Gastroenterologie·2026
Same journal

[Updated S3 guideline on ulcerative colitis].

Zeitschrift fur Gastroenterologie·2026
Same journal

Zeitschrift fur Gastroenterologie·2026
Same journal

Zeitschrift fur Gastroenterologie·2026
See all related articles

Related Experiment Video

Updated: Jun 16, 2026

A Mouse Model of Intestinal Partial Obstruction
07:33

A Mouse Model of Intestinal Partial Obstruction

Published on: March 5, 2018

[Malignant bowel obstruction].

M Zorn1, D Domagk, T Auerbauch

  • 1Medizinische Klinik I (Schwerpunkte Gastroenterologie, Stoffwechsel, Infektiologie, Onkologie und Palliativmedizin), St.-Vincenz-Krankenhaus, Datteln, Germany.

Zeitschrift Fur Gastroenterologie
|February 4, 2010
PubMed
Summary
This summary is machine-generated.

Malignant bowel obstruction (MBO) is a common complication in advanced cancer, posing a significant challenge in palliative care. This review highlights the gastroenterology role in managing MBO, focusing on symptom relief through surgical, endoscopic, and medical interventions.

More Related Videos

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
07:44

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

Murine Mesenteric Lymphadenectomy for Selective Disruption of Lymphatic Communication with Region-Specific Gut
07:27

Murine Mesenteric Lymphadenectomy for Selective Disruption of Lymphatic Communication with Region-Specific Gut

Published on: December 30, 2025

Related Experiment Videos

Last Updated: Jun 16, 2026

A Mouse Model of Intestinal Partial Obstruction
07:33

A Mouse Model of Intestinal Partial Obstruction

Published on: March 5, 2018

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
07:44

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

Murine Mesenteric Lymphadenectomy for Selective Disruption of Lymphatic Communication with Region-Specific Gut
07:27

Murine Mesenteric Lymphadenectomy for Selective Disruption of Lymphatic Communication with Region-Specific Gut

Published on: December 30, 2025

Area of Science:

  • Palliative Care
  • Gastroenterology
  • Oncology

Background:

  • Malignant bowel obstruction (MBO) is a frequent complication in patients with progressive malignant disorders.
  • MBO presents a major interdisciplinary challenge, particularly within palliative care settings.
  • Gastroenterology is central to the multidisciplinary management of MBO.

Observation:

  • Diagnostic work-up is crucial for MBO management.
  • Defining treatment goals with patients and families is essential, prioritizing symptom relief.
  • Surgical, endoscopic, and medical therapeutic options exist for MBO.

Findings:

  • Malignant bowel obstruction is increasingly recognized as a distinct clinical entity in international literature.
  • Case reports illustrate various therapeutic approaches for MBO.
  • This review aims to introduce MBO as a distinct entity within the German medical literature.

Implications:

  • Enhanced recognition of MBO as a distinct entity can improve patient care and research.
  • A multidisciplinary approach focusing on symptom management is vital for patients with MBO.
  • Standardizing MBO management strategies across different medical communities is important.