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Updated: Jun 16, 2026

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
Published on: October 11, 2024
Paraganglioma resection requiring left atrial reconstruction
John Petersen1, Gary Cooper, Peter Drew
1Divisions of Cardiology, Pathology, and Thoracic and Cardiovascular Surgery, University of Florida, Gainesville, FL 32610, USA. john.petersen@medicine.ufl.edu
Extra-adrenal pheochromocytomas (paragangliomas) rarely invade the heart. A novel bioabsorbable matrix successfully replaced a paraganglioma invading the left atrium.
Area of Science:
- Cardiovascular Surgery
- Surgical Oncology
- Endocrinology
Background:
- Paragangliomas, or extra-adrenal pheochromocytomas, originate from autonomic ganglia chromaffin cells.
- While mediastinal paragangliomas are known, cardiac invasion is exceptionally rare.
- These tumors can secrete catecholamines, posing significant clinical challenges.
Observation:
- A rare case of a paraganglioma invading the posterior left atrium is presented.
- The tumor's location posed a complex surgical challenge due to its proximity to cardiac structures.
Findings:
- A novel bioabsorbable matrix was utilized for reconstruction.
- The matrix successfully replaced the resected tumor segment in the left atrium.
- This technique facilitated tumor removal while preserving cardiac function.
Implications:
- This approach offers a potential solution for managing rare cardiac-invasive paragangliomas.
- The use of bioabsorbable matrices may represent a significant advancement in complex cardiac tumor reconstruction.
- Further research is warranted to evaluate the long-term efficacy and safety of this technique.
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