Use of chain transfer agent attached to silica particles in preparation of polystyrene-based stationary phases
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Updated: Jun 16, 2026

Preparation of Poly(pentafluorophenyl acrylate) Functionalized SiO2 Beads for Protein Purification
Published on: November 19, 2018
Dong Guk Hwang1, Shabi Abbas Zaidi, Won Jo Cheong
1Department of Chemistry, Nano Fine Center, and Institute of Basic Research, Inha University, Incheon, South Korea.
Abstract:
A new stationary phase has been prepared by attaching a new chain transfer agent on silica particles followed by reversible addition-fragmentation chain transfer polymerization. Porous silica particles were reacted with 3-chloropropyltrimethoxysilane followed by sodium diethyl dithiocarbarmate. The silica particles were then allowed to undergo radical polymerization with styrene. The phase had improved ligand morphology to show better separation performance than that of the conventional C18 phase.
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