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Updated: Jun 16, 2026
The Impact of Motor Task Conditions on Goal-Directed Arm Reaching Kinematics and Trunk Compensation in Chronic Stroke Survivors
Published on: May 2, 2021
The relationship between fatigue, aerobic fitness, and motor control in people with chronic stroke: a pilot study
Benjamin Y Tseng1, Patricia Kluding
1Department of Physical Therapy and Rehabilitation Sciences, University of Kansas Medical Center, Mail Stop 3051, 3901 Rainbow Blvd, Kansas City, KS 66160, USA.
Background:
Fatigue is a commonly neglected issue despite the high incidence rate reported in people post-stroke.
Objective:
To explore the relationship between fatigue, aerobic fitness, and motor control in people with chronic stroke.
Methods:
Nine people post-stroke participated in this cross-sectional study (7 females, mean age = 56.8 (11.8) years, range 47-73, time post-stroke = 47.6 (51.2) months, range 11-140). Participants performed a six-minute-walk exercise in order to induce fatigue, followed immediately by a Fatigue Index (FI) scale to report fatigue at the moment. The distance walked (6MWD) was documented. On a separate visit, aerobic fitness was characterized by VO(2Peak) using a cycle-ergometer. In addition, Fugl-Meyer (FM) test was administered to assess motor control of the hemiparetic side. Pearson Product Correlation Coefficient and multiple linear regression were used to analyze the relationships between FI, VO(2Peak) and FM.
Results:
VO(2Peak) showed significant positive correlations with FM (r = .779, p = .013) and 6MWD (r = .726, p = .027). Fatigue index displayed significant negative correlations with VO(2Peak) (r = -.739, p = .023) and FM (r = -.873, p = .002), but not with 6MWD (r = -.620, p = .075). Using stepwise multiple regression, we found that that FM was an independent predictor of FI (p = .002) and explained 76.2% of variance in FI (R2 = .762).
Conclusion:
Our data suggests that motor control capability may be a good predictor of fatigue in people post-stroke. Fatigue is a complex phenomenon; a quantifiable measure that is sensitive to multiple components is needed in order to distinguish the nature of fatigue and its contributing factors.
