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Updated: Jun 16, 2026

Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
[Inflammatory bowel disease and pregnancy].
Elena Garrido1, Manuel Van Domselaar, Sara Morales
1Consulta de Enfermedad Inflamatoria Intestinal, Servicio de Gastroenterología, Hospital Ramón y Cajal, Madrid, España.
Planning pregnancy with inflammatory bowel disease (IBD) requires careful consideration. Most IBD medications are safe during pregnancy, but methotrexate should be avoided. Achieving IBD remission before conception is strongly recommended for optimal outcomes.
Area of Science:
- Gastroenterology
- Obstetrics
- Reproductive Medicine
Context:
- Investigates the complex interplay between inflammatory bowel disease (IBD) and pregnancy.
- Addresses the clinical challenges arising from the coexistence of IBD and gestation.
Purpose:
- To analyze the mutual influence of IBD and pregnancy.
- To evaluate the impact of IBD and its treatments on reproductive health, delivery, and breastfeeding.
- To provide guidance on managing IBD during pregnancy.
Summary:
- Recommends achieving IBD remission prior to conception for improved maternal and fetal outcomes.
- Highlights that most IBD pharmacotherapies are safe for use during pregnancy and breastfeeding.
- Identifies methotrexate as a notable exception, contraindicated during pregnancy.
Impact:
- Informs clinical decision-making for managing IBD in pregnant patients.
- Supports the ability of patients with IBD to have successful pregnancies and limit reproductive concerns.
- Emphasizes that IBD does not necessitate limitations on fertility or sexual health.
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