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Updated: Jun 16, 2026

Immobilization of Caenorhabditis elegans to Analyze Intracellular Transport in Neurons
Published on: October 18, 2017
Caulimoviridae tubule-guided transport is dictated by movement protein properties
Jesús Sánchez-Navarro1, Thor Fajardo, Stefania Zicca
1Istituto di Virologia Vegetale, Consiglio, Nazionale delle Ricerche, Via Amendola 165/A, 70126 Bari, Italy.
Abstract:
Plant viruses move through plasmodesmata (PD) either as nucleoprotein complexes (NPCs) or as tubule-guided encapsidated particles with the help of movement proteins (MPs). To explore how and why MPs specialize in one mechanism or the other, we tested the exchangeability of MPs encoded by DNA and RNA virus genomes by means of an engineered alfalfa mosaic virus (AMV) system. We show that Caulimoviridae (DNA genome virus) MPs are competent for RNA virus particle transport but are unable to mediate NPC movement, and we discuss this restriction in terms of the evolution of DNA virus MPs as a means of mediating DNA viral genome entry into the RNA-trafficking PD pathway.
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