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Contrast sensitivity changes in background diabetic retinopathy.

P K Khosla1, D Talwar, H K Tewari

  • 1Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi.

Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie
|February 1, 1991
PubMed
Summary
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Diabetic patients with retinopathy show significantly reduced contrast sensitivity. This visual impairment, measurable with Cambridge charts, may aid early screening for diabetic retinopathy in primary care settings.

Area of Science:

  • Ophthalmology
  • Diabetology
  • Visual Neuroscience

Background:

  • Conflicting reports exist regarding contrast sensitivity in diabetic patients.
  • Diabetic retinopathy is a significant complication of diabetes mellitus.
  • Early detection of diabetic retinopathy is crucial for preventing vision loss.

Purpose of the Study:

  • To evaluate contrast sensitivity in diabetic patients with and without retinopathy.
  • To compare contrast sensitivity between diabetic patients and age-matched controls.
  • To assess the utility of contrast sensitivity testing for screening diabetic retinopathy.

Main Methods:

  • Contrast sensitivity was assessed using Cambridge low-contrast sensitivity charts.
  • Participants included 22 diabetic patients (22 eyes without retinopathy, 16 eyes with background retinopathy) and 10 control subjects (20 eyes).

Related Experiment Videos

  • Fluorescein angiography was used to confirm the presence of retinopathy.

    • Main Results:

    • Mean contrast threshold at 4 cycles/degree was 0.46% (diabetic without retinopathy), 0.60% (diabetic with retinopathy), and 0.43% (controls).
    • Contrast sensitivity was significantly lower in diabetic eyes with retinopathy compared to normal eyes (p=0.011) and diabetic eyes without retinopathy (p=0.033).

    Conclusions:

    • Diabetic patients with retinopathy exhibit significantly impaired contrast sensitivity.
    • Contrast sensitivity testing may serve as a valuable screening tool for diabetic retinopathy in primary care.
    • Further research can explore the integration of contrast sensitivity tests into routine diabetic care.