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Updated: Jun 16, 2026

A Delayed Inoculation Model of Chronic Pseudomonas aeruginosa Wound Infection
Published on: February 20, 2020
A case of necrotising fasciitis caused by Pseudomonas aeruginosa
1Department of Trauma and Orthopaedic Surgery, Royal Berkshire Hospital NHS FoundationTrust, Reading, England.
Abstract:
Necrotising fasciitis is a rare but severe infection of soft-tissue associated with rapid progression, systemic toxicity and high mortality. Monomicrobial necrotising fasciitis caused by Pseudomonas aeruginosa is exceptionally uncommon with only 12 cases reported in the literature. We describe a fatal case with an atypical presentation in a patient following spinal decompression for a metastasis from prostate cancer.
Insights
Necrotising fasciitis is a severe soft-tissue infection. This case highlights an exceptionally rare Pseudomonas aeruginosa monomicrobial necrotising fasciitis in a patient with prostate cancer metastasis.
Area of Science:
- Infectious Diseases
- Surgical Complications
- Oncology
Background:
- Necrotising fasciitis is a severe, rapidly progressing soft-tissue infection with high mortality.
- Monomicrobial necrotising fasciitis is rare, with Pseudomonas aeruginosa infections being exceptionally uncommon.
Observation:
- A patient with metastatic prostate cancer developed necrotising fasciitis following spinal decompression surgery.
- The presentation was atypical, complicating diagnosis and treatment.
Findings:
- The patient succumbed to the infection, indicating a fatal outcome.
- This case represents one of the few documented instances of monomicrobial necrotising fasciitis caused by Pseudomonas aeruginosa.
Implications:
- This case underscores the importance of considering rare pathogens in severe soft-tissue infections, especially in immunocompromised patients.
- It highlights potential complications following spinal surgery in cancer patients.
- Further research into Pseudomonas aeruginosa necrotising fasciitis pathogenesis and treatment is warranted.
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