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Updated: Jun 16, 2026

Ultra-Fast Amplicon-Based Next-Generation Sequencing in Non-Squamous Non-Small Cell Lung Cancer
Published on: September 8, 2023
Evolution of therapy decision-making process for advanced non-small cell lung cancer
Vittorio Gebbia1, Gianfranco Mancuso, Lucia Lombardi
1Department of Experimental Oncology and Medical Applications (DOSAC), University of Palermo, and Medical Oncology Division, La Maddalena Clinic for Cancer, Palermo, Italy. vittorio.gebbia@tin.it
Abstract:
Advanced non-small cell lung cancer remains a lethal disease with poor prognosis. In the last decades results of systemic chemotherapy have reached a disappointing plateau without significant differences between the most widely employed third-generation regimens. Recent scientific evidence has shed new light on the management of advanced non-small cell lung cancer, especially for the important role of histological definition in therapy-planning process. The results of new biologic agents are also reported as are the promising data on pharmacogenomic-guided treatment.
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