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Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
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Published on: September 15, 2017

Links between behavioral factors and inflammation.

M-F O'Connor1, M R Irwin

  • 1Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, California, USA. mfoconnor@mednet.ucla.edu

Clinical Pharmacology and Therapeutics
|February 5, 2010
PubMed
Summary
This summary is machine-generated.

Biobehavioral factors like diet, smoking, exercise, and sleep significantly impact inflammation markers. Lifestyle interventions targeting these factors may enhance anti-inflammatory treatments.

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A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
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Last Updated: Jun 16, 2026

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
12:50

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response

Published on: September 15, 2017

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
09:52

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites

Published on: August 8, 2014

Area of Science:

  • Integrative biology and health sciences
  • Behavioral medicine and public health

Background:

  • Chronic inflammation is a key factor in numerous diseases.
  • Biobehavioral factors are increasingly recognized as significant modulators of inflammatory processes.
  • Understanding these links is crucial for developing holistic health strategies.

Purpose of the Study:

  • To review robust associations between key biobehavioral factors and inflammation markers.
  • To highlight the potential of lifestyle interventions in managing inflammation.
  • To provide a foundation for integrating behavioral strategies with medical treatments.

Main Methods:

  • Comprehensive literature review of epidemiological, clinical, and experimental studies.
  • Analysis of data linking diet, smoking, coffee, alcohol, exercise, and sleep disruption to inflammation.
  • Synthesis of evidence on the impact of these variables on inflammatory markers.

Main Results:

  • Diet, smoking, coffee consumption, alcohol intake, physical activity, and sleep disruption demonstrate significant associations with inflammation markers.
  • These biobehavioral factors are modifiable and represent potential targets for intervention.
  • Evidence supports the role of these factors across diverse populations and health conditions.

Conclusions:

  • Biobehavioral factors are critical, modifiable determinants of inflammation.
  • Targeting lifestyle behaviors offers a promising complementary approach to anti-inflammatory pharmacotherapy.
  • Integrating behavioral interventions can enhance overall treatment efficacy for inflammatory conditions.