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Related Concept Videos

American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
Cholera01:25

Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Riboswitches01:56

Riboswitches

Riboswitches are non-coding mRNA domains that regulate the transcription and translation of downstream genes without the help of proteins. Riboswitches bind directly to a metabolite and can form unique stem-loop or hairpin structures in response to the amount of the metabolite present. They have two distinct regions – a metabolite-binding aptamer and an expression platform.
The aptamer has high specificity for a particular metabolite which allows riboswitches to specifically regulate...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
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Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

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Related Experiment Video

Updated: Jun 16, 2026

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates
13:55

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates

Published on: January 27, 2019

[Chagas Carlos Justiniano Ribeiro (1879-1934)].

J F Pays1

  • 1Université del Nordeste, Argentine. pays@necker.fr

Bulletin De La Societe De Pathologie Exotique (1990)
|February 5, 2010
PubMed
Summary
This summary is machine-generated.

Carlos Chagas dedicated his life to studying American Trypanosomiasis, caused by Trypanosoma cruzi. His significant contributions to tropical medicine, despite facing criticism, cemented his legacy.

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Last Updated: Jun 16, 2026

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates
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Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates

Published on: January 27, 2019

Parasite Induced Genetically Driven Autoimmune Chagas Heart Disease in the Chicken Model
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Area of Science:

  • Tropical Medicine
  • Parasitology
  • Medical History

Background:

  • Carlos Chagas's lifelong dedication to understanding American Human Trypanosomiasis.
  • The causative agent, Trypanosoma cruzi, and its impact on public health.
  • Historical context of Chagas's scientific career and recognition.

Discussion:

  • Analysis of the critical reception Carlos Chagas faced during his lifetime.
  • The evolving understanding and management of Chagas disease globally.
  • The significance of Chagas's work in the field of infectious diseases.

Key Insights:

  • Carlos Chagas is central to the discovery and study of American Trypanosomiasis.
  • Despite contemporary criticism, his work is now globally recognized.
  • The increasing concern of Chagas disease in non-endemic regions necessitates public health interventions.

Outlook:

  • Continued research into Trypanosoma cruzi and Chagas disease.
  • The importance of historical perspectives in understanding scientific progress.
  • Global public health strategies for managing neglected tropical diseases.