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Related Concept Videos

Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Methods Of Healthcare Delivery System01:26

Methods Of Healthcare Delivery System

At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is limited...
Bioequivalence studies: Biowaivers01:13

Bioequivalence studies: Biowaivers

In certain scenarios, in vitro dissolution tests can replace in vivo bioequivalence studies. This is particularly true when a drug product, though available in varying strengths, maintains proportional similarity in its active and inactive ingredients. In such cases, the need for in vivo bioequivalence studies for lower strength variants may be waived, provided dissolution tests and in vivo studies on the highest strength yield satisfactory results.Bioequivalence can be indicated through...
Bioavailability Study Design: Healthy Subjects Versus Patients01:15

Bioavailability Study Design: Healthy Subjects Versus Patients

Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
Principles of Disease Surveillance01:26

Principles of Disease Surveillance

Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
Preventive Healthcare Services01:30

Preventive Healthcare Services

Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:

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Related Experiment Video

Updated: Jun 16, 2026

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
23:56

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

Hemovigilance in developing countries.

Yasmin Ayob1

  • 1National Blood Centre, Jalan Tun Razak, Kuala Lumpur, Malaysia. yasminayob52@yahoo.com

Biologicals : Journal of the International Association of Biological Standardization
|February 6, 2010
PubMed
Summary

Implementing hemovigilance programs in developing countries is challenging due to fragmented blood transfusion services. However, adapting models and utilizing available resources can improve blood supply safety and sufficiency.

Area of Science:

  • Public Health
  • Health Services Research
  • Blood Transfusion Services

Background:

  • Hemovigilance and quality systems are standard in developed countries' blood transfusion services (BTS).
  • Developing nations face challenges in donor recruitment, blood supply sufficiency, and safety.
  • Fragmented BTS in developing countries complicates national hemovigilance program implementation.

Purpose of the Study:

  • To explore the feasibility and adaptation of hemovigilance programs in developing countries.
  • To identify strategies for improving blood supply safety and sufficiency in resource-limited settings.
  • To highlight the importance of data collection and utilization for effective interventions.

Main Methods:

  • Review of existing hemovigilance models and their successes/failures in developing countries.

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  • Analysis of resource limitations and expertise gaps in developing nations' BTS.
  • Identification of alternative monitoring tools suitable for developing country contexts.

    • Main Results:

    • While direct implementation of developed-country models is difficult, some developing countries have established effective blood programs.
    • Collected hemovigilance data, despite deficiencies, offers valuable insights for health authorities.
    • Available resources should prioritize addressing apparent deficiencies in blood transfusion services.

    Conclusions:

    • Adaptable hemovigilance strategies are crucial for improving blood safety in developing countries.
    • Accurate data collection and its integration into policy-making are essential for interventions.
    • Phased implementation of surveillance programs aligned with BTS development is recommended.