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Updated: Jun 16, 2026
08:56
Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation
Published on: September 24, 2021
Intrapericardial triamcinolone for acute pericarditis after electrophysiologic procedures.
Carleton B Maxwell1, Michael A Crouch
1Jackson-Madison County General Hospital, 620 Skyline Drive, Jackson, TN 38301, USA. carleton.maxwell@wth.org
Summary
Intrapericardial triamcinolone may effectively treat acute pericarditis following electrophysiologic procedures. This approach reduced pain and inflammation in most patients, though further research is needed.
Area of Science:
- Cardiology
- Pharmacology
Background:
- Acute pericarditis is an inflammation of the pericardium, often managed with NSAIDs and colchicine.
- Oral corticosteroids are generally reserved for refractory cases due to recurrence risks.
- Intrapericardial triamcinolone is an infrequently used but guideline-recommended option for select pericarditis cases.
Observation:
- This case series examined three patients with pericarditis or tamponade post-electrophysiologic procedures.
- Patients received intrapericardial triamcinolone in doses ranging from 50 to 200 mg.
- Two patients experienced significant reductions in pain and need for analgesics.
Findings:
- Intrapericardial triamcinolone administration led to decreased pain and reduced need for pain medication in two of three patients.
- The third patient showed a reduced need for supportive therapy, but not a complete resolution.
- The study suggests potential efficacy but highlights the need for further investigation.
Implications:
- Intrapericardial triamcinolone may be a viable treatment for acute pericarditis after electrophysiologic procedures.
- Further research is required to establish optimal dosing and long-term outcomes.
- Individual patient factors, such as medical history and renal function, should guide treatment decisions.
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