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Investigating the Immunological Mechanisms Underlying Organ Transplant Rejection
05:10

Investigating the Immunological Mechanisms Underlying Organ Transplant Rejection

Published on: August 20, 2007

Mechanisms involved in antibody- and complement-mediated allograft rejection

Barbara A Wasowska1

  • 1Department of Pathology, The Johns Hopkins University School of Medicine, Ross Bldg. 664B, Baltimore, MD 21205, USA. bwasowsk@jhmi.edu

Immunologic Research
|February 6, 2010
PubMed
Summary

Antibody-mediated rejection causes allograft loss and is resistant to therapy. This review explores complement pathways and effector cell interactions in antibody-mediated endothelial cell injury during organ transplantation.

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