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Updated: Jun 16, 2026

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[Desmopressin (Minirin) in multiple trauma--a case report].

P Hilbert1, M F Struck, R Stuttmann

  • 1Klinik für Anästhesiologie, Intensiv- und Notfallmedizin, BG-Kliniken Bergmannstrost, Halle. dr.peterhilbert@web.de

Zeitschrift Fur Orthopadie Und Unfallchirurgie
|February 6, 2010
PubMed
Summary

Desmopressin effectively controlled diffuse bleeding in two trauma patients experiencing hypothermia and acidosis. This study highlights its potential therapeutic role in managing complex bleeding complications in trauma care.

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Area of Science:

  • Trauma care
  • Hemorrhage management
  • Coagulation disorders

Background:

  • Trauma patients frequently exhibit bleeding and clotting disturbances.
  • Hypothermia, acidosis, and coagulopathy complicate trauma management.
  • Early and effective therapy is crucial for these patients.

Observation:

  • Two trauma patients presented with diffuse bleeding.
  • These patients had coexisting hypothermia and acidosis.
  • Desmopressin was administered to manage the bleeding.

Findings:

  • Desmopressin administration was successful in controlling diffuse bleeding in both cases.
  • The authors observed a positive response to desmopressin in this specific trauma context.
  • Advantages and disadvantages of desmopressin use were evaluated in these patients.

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Implications:

  • Desmopressin may be a viable therapeutic option for diffuse bleeding in trauma patients with specific pathophysiological conditions.
  • Further research is warranted to establish the optimal use of desmopressin in trauma-induced coagulopathy.
  • This case series contributes to understanding desmopressin's role in managing complex bleeding scenarios in critical care settings.