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Related Experiment Video

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Assessing Burrowing, Nest Construction, and Hoarding in Mice

Assessing Burrowing, Nest Construction, and Hoarding in Mice

Published on: January 5, 2012

Treatment of hoarding.

Randy O Frost¹

¹Department of Psychology, 44 College Lane, Smith College, Northampton, MA 01063, USA. rfrost@smith.edu

Expert Review of Neurotherapeutics

|February 9, 2010

Summary

Hoarding disorder is a frequent mental health condition with limited treatment success. While serotonin-reuptake inhibitors and standard cognitive-behavioral therapy are largely ineffective, hoarding-focused cognitive-behavioral therapy shows promise.

Area of Science:

Psychiatry
Clinical Psychology
Behavioral Science

Background:

Hoarding disorder is a significant and increasingly recognized psychopathology.
Current treatment approaches for hoarding disorder have shown limited efficacy.
Existing research on pharmacological and psychological interventions is often methodologically flawed.

Purpose of the Study:

To evaluate the effectiveness of different treatment modalities for hoarding disorder.
To clarify the efficacy of serotonin-reuptake inhibitors (SRIs) in treating hoarding disorder.
To assess the utility of cognitive-behavioral therapy (CBT) approaches for hoarding disorder.

Main Methods:

Review of existing studies on pharmacological treatments, including serotonin-reuptake inhibitors.

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Assessing Burrowing, Nest Construction, and Hoarding in Mice

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Analysis of cognitive-behavioral treatments originally developed for obsessive-compulsive disorder.

Examination of emerging cognitive-behavioral models specifically designed for hoarding disorder.

Main Results:

Most studies indicate a poor response to serotonin-reuptake inhibitors in hoarding disorder patients.
Methodological limitations in SRI studies prevent definitive conclusions about their efficacy.
Cognitive-behavioral treatments for obsessive-compulsive disorder have demonstrated poor outcomes in hoarding disorder.
A cognitive-behavioral model tailored to hoarding disorder shows encouraging preliminary results.

Conclusions:

The true efficacy of serotonin-reuptake inhibitors for hoarding disorder remains largely undetermined due to study limitations.
Standard cognitive-behavioral treatments for OCD are not effective for hoarding disorder.
Hoarding-specific cognitive-behavioral therapy presents a promising avenue for future treatment development.