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Related Experiment Video

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Self-Administration of Drugs in Mouse Models of Feeding and Obesity

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Published on: June 8, 2021

Self-reported side effects in children and adolescents taking risperidone.

Simon Byrne¹, Garry Walter, Glenn Hunt

¹Northern Sydney Central Coast Health, NSW, Australia.

Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists

|February 9, 2010

Summary

Young individuals generally tolerate low-dose risperidone well, but prolonged use correlates with increased side effects, especially psychic and extrapyramidal symptoms. Monitoring is crucial for long-term treatment.

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Published on: November 21, 2013

Area of Science:

Psychiatry
Pediatric Pharmacology

Background:

Risperidone is frequently prescribed for young people.
Understanding medication side effects in this demographic is crucial for safe and effective treatment.

Purpose of the Study:

To describe medication side effects in young patients using low-dose risperidone.
To assess the relationship between duration of risperidone use and side effect severity.

Main Methods:

A cross-sectional study involving 66 patients aged 6-18 years.
Utilized the Liverpool University Neuroleptic Side Effect Rating Scale (LUNSERS) for self-reporting.
Included patients on low-dose risperidone, alone or with other medications, for up to 13 years.

Main Results:

Overall good tolerance to low-dose risperidone was observed.
Longer exposure to risperidone was linked to increased side effect levels.
Psychic (e.g., tiredness, concentration/memory issues, increased dreaming) and extrapyramidal side effects were most notable.

Conclusions:

Clinicians should actively monitor for side effects in young patients on low-dose risperidone.
Vigilance is particularly important for patients on extended medication regimens.
Regular assessment of side effects is recommended for all psychotropic medications in youth.