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Updated: Jun 16, 2026

Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex
Published on: July 4, 2018
Sedoanalgesia in paediatric intensive care: a survey of 19 Italian units
F Benini1, M Farina1, A Capretta1
1Department of Pediatrics, University of Padova, Padova, ItalyMayer Children Hospital, Florence, Italy.
Aim:
To analyse the methods used to manage and monitor sedoanalgesia at Italian paediatric intensive care units (ICUs).
Methods:
Data were collected by administering a questionnaire that aimed to investigate whether ICUs adopted a validated protocol to manage sedoanalgesia.
Results:
The results revealed that a majority of the ICUs adopt a protocol for dealing with sedation and analgesia, but this protocol is implemented with difficulty or not at all in routine clinical practice. The most often used pharmacological combination, is midazolam and fentanyl. Several weaknesses remain in terms of the methods used to assess sedoanalgesia, which are generally not standardized, but rather based on recording the patient's physiological parameters.
Conclusion:
Sedation and analgesia are priority issues in the management of critically ill children. None of the numerous drugs available is ideal and the protocols currently used in clinical practice involve the combined use of different drugs. There is currently no shared and validated approach as to which is the most effective and safest sedoanalgesic regimen in critically ill children.
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