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BIPP induced methaemoglobinaemia.

A Nigam1, J Ruddy, P E Robin

  • 1Department of Otlaryngology, Dudley Road Hospital, Birmingham.

The Journal of Laryngology and Otology
|February 1, 1991
PubMed
Summary
This summary is machine-generated.

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Bismuth subnitrate in BIPP nasal packing rarely causes significant methaemoglobinaemia. Routine use of BIPP (Bismuth Iodoform Paraffin Paste) in nasal packing is unlikely to lead to abnormal methaemoglobin levels.

Area of Science:

  • Otolaryngology
  • Clinical Pharmacology

Background:

  • Bismuth subnitrate, a component of BIPP, is a known cause of methaemoglobinaemia.
  • Nasal packing with BIPP is a common otolaryngological procedure.

Purpose of the Study:

  • To investigate the risk of methaemoglobinaemia from BIPP nasal packing.
  • To assess methaemoglobin levels in patients undergoing nasal packing with BIPP.

Main Methods:

  • Ten patients undergoing nasal packing with BIPP-impregnated gauze were recruited.
  • Blood samples were taken to measure methaemoglobin levels pre- and post-procedure.

Main Results:

  • Only one patient showed elevated methaemoglobin levels.
  • This abnormality was likely due to the large quantity of BIPP used in that specific case.

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Conclusions:

  • Significant methaemoglobinaemia is unlikely with routine BIPP nasal packing.
  • The risk appears minimal under standard clinical practice.