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Antiasthma Drugs: β2-Adrenoceptor Agonists01:25

Antiasthma Drugs: β2-Adrenoceptor Agonists

Bronchodilators are critical in managing asthma, a chronic respiratory condition characterized by airway constriction due to inflammation and hyper-reactivity. Specifically, bronchodilators ease this constriction by relaxing the bronchial muscles, facilitating easier breathing.
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Adrenergic Antagonists: ɑ and β-Receptor Blockers

Third-generation β-blockers, such as labetalol and carvedilol, represent a significant advancement in managing cardiovascular conditions. Unlike conventional β-blockers, which can induce peripheral vasoconstriction, third-generation drugs block α1 adrenoceptors. This promotes vasodilation through several mechanisms, such as increased nitric oxide production, inhibition of calcium ion entry, opening of potassium ion channels, and antioxidant action. Labetalol, for instance, is clinically...
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Drugs for Treatment of Ulcerative Colitis in IBD

Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide generation. 
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Antiasthma Drugs: Leukotriene Modifiers

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Anxiolytic Drugs: Benzodiazepines and Buspirone

Benzodiazepines are a class of anxiolytic drugs known for their rapid efficacy and high therapeutic-to-lethal dose ratio, but with a potential risk of drug dependence. These drugs are lipophilic, allowing for rapid absorption after oral administration, eventually reaching the central nervous system (CNS). Once in the CNS, benzodiazepines bind to the allosteric site of the GABAA receptor. This binding enhances the inhibitory effects of the neurotransmitter GABA. By doing so, they prevent...
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Antiasthma Drugs: Muscarinic Receptor Antagonists

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Updated: Jun 16, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Bisabolol.

Kathryn Russell1, Sharon E Jacob

  • 1Department of Medicine, University of California, San Diego School of Medicine, San Diego, CA, USA.

Dermatitis : Contact, Atopic, Occupational, Drug
|February 9, 2010
PubMed
Summary
This summary is machine-generated.

Bisabolol, a chamomile extract with anti-inflammatory benefits, can cause allergic contact dermatitis. Patch testing is recommended for patients with suspected reactions to bisabolol in skin products.

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Last Updated: Jun 16, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Area of Science:

  • Dermatology and Phytochemistry

Background:

  • Bisabolol, a natural extract from German chamomile, is widely used in cosmetics for its anti-inflammatory and skin-soothing properties.
  • Its presence in numerous personal care products, including creams, lotions, sunscreens, and makeup, raises awareness of potential adverse reactions.
  • Reports of contact dermatitis linked to bisabolol have emerged from Europe and are suspected in the United States.

Purpose of the Study:

  • To investigate the role of bisabolol as a potential allergen in contact dermatitis.
  • To evaluate the utility of patch testing for diagnosing bisabolol-induced skin reactions.
  • To inform clinical management of patients with suspected bisabolol sensitivity.

Main Methods:

  • Review of reported cases and clinical observations regarding bisabolol and contact dermatitis.
  • Discussion of the diagnostic value of patch testing with bisabolol or bisabolol-containing products.
  • Clinical counseling recommendations for patients identified as sensitized to bisabolol.

Main Results:

  • Bisabolol is identified as a potential contact allergen responsible for dermatitis.
  • Patch testing can be a valuable diagnostic tool for identifying bisabolol sensitivity.
  • Patients with confirmed bisabolol allergy require avoidance of products containing this ingredient.

Conclusions:

  • Bisabolol can induce allergic contact dermatitis, necessitating clinical awareness.
  • Patch testing is a crucial method for diagnosing bisabolol allergy in dermatology.
  • Educating sensitized patients on product avoidance is essential for managing their condition.