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Updated: Jun 16, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit

Published on: July 13, 2019

A multimodal approach to central venous catheter hub care can decrease catheter-related bloodstream infection.

Sulaiman Sannoh¹, Barbara Clones, Jose Munoz

¹Division of Neonatology, Regional Children's Hospital, Cooper University Hospital, Camden, NJ 08103, USA. fanta_sannoh@yahoo.com

American Journal of Infection Control

|February 9, 2010

Summary

This summary is machine-generated.

A multimodal intervention significantly reduced catheter-related bloodstream infections (CRBSIs) in neonates. This evidence-based approach, including chlorhexidine hub care and staff education, proved effective and cost-saving.

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Published on: January 13, 2026

Area of Science:

Neonatal intensive care
Infection control
Public health

Background:

Catheter-related bloodstream infections (CRBSIs) pose a significant risk in neonatal intensive care units.
Evidence-based interventions are crucial for reducing healthcare-associated infections.

Purpose of the Study:

To investigate the effectiveness of a multimodal intervention in decreasing CRBSIs in neonates.
To evaluate the impact of improved central venous catheter (CVC) hub care on infection rates.

Main Methods:

Prospective interventional study involving neonates with CVCs.
Implementation of a multimodal approach including 2% chlorhexidine in 70% isopropyl alcohol for CVC hub care.
Audiovisual education provided to medical staff, with pre- and post-intervention CRBSI rate comparison.

Main Results:

Significant reductions in CRBSI rates observed for all catheter types (umbilical catheters and peripherally inserted central catheters).
CRBSI rates decreased from 15/1000 to 10/1000 catheter-days for umbilical catheters and 23/1000 to 10/1000 catheter-days for PICCs.
Sustained CRBSI reduction and decreased incidence of gram-negative septicemia, preventing 10 CRBSIs and yielding cost savings.

Conclusions:

The multimodal intervention effectively decreased CRBSI rates across all catheter types and birth weight categories.
Audiovisual education is a valuable tool for implementing practice changes in infection control.
Continuous reeducation and compliance monitoring are essential for preventing nosocomial infections and reducing healthcare costs.