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Sleep and body mass index in depressed children and healthy controls

Julita Wojnar1, Kirk J Brower, Richard Dopp

  • 1University of Michigan, Department of Psychiatry, Ann Arbor, MI, USA.

Sleep Medicine
|February 9, 2010
PubMed

Insights

Children with major depressive disorder (MDD) and high body mass index (BMI) experience more fragmented sleep. Addressing both sleep and weight is crucial for managing pediatric MDD.

Area of Science:

  • Pediatric Sleep Medicine
  • Child and Adolescent Psychiatry
  • Obesity Research

Background:

  • Higher body mass index (BMI) is linked to sleep disturbances and depressive symptoms.
  • The combined impact of depression and BMI on sleep in children remains understudied.

Purpose of the Study:

  • To investigate the relationship between BMI and polysomnography findings in children with major depressive disorder (MDD).
  • To compare sleep patterns in children with MDD and high BMI versus healthy controls (HCs).

Main Methods:

  • A sample of 104 children (8-17 years) including 72 with MDD and 32 HCs.
  • BMI was categorized using CDC percentiles (normal vs. high weight).
  • Polysomnography data were analyzed, adjusting for sex and Tanner stage.

Main Results:

  • In the MDD group, higher BMI correlated with reduced sleep efficiency, REM sleep percentage, and increased time awake and moving.
  • High-weight children with MDD showed fragmented sleep and altered REM sleep patterns compared to HC.
  • High-weight MDD group had increased time awake and moving, while high-weight HC group showed a decrease.

Conclusions:

  • Children and adolescents with MDD and high BMI exhibit more fragmented sleep.
  • Interventions targeting both sleep and weight are recommended for the management of pediatric MDD.
  • Findings suggest a normalization of REM sleep patterns in high-weight children with MDD.
Abstract

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