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Updated: Jun 16, 2026

CorrelationCalculator and Filigree: Tools for Data-Driven Network Analysis of Metabolomics Data
Published on: November 10, 2023
Linked metabolites: a tool for the construction of directed metabolic graphs
John M Easton1, Lisa M Harris, Mark R Viant
1School of Electronic, Electrical and Computer Engineering, University of Birmingham, Edgbaston, Birmingham, UK.
Abstract:
Metabolic pathway diagrams provide a wealth of information on how reactions combine to perform biological functions. While pathway diagrams are arranged in a way that allows a specific area of metabolism to be visualised, the inherent complexity of each pathway makes it difficult to identify the sets of reactions linking groups of compounds; a common task for researchers attempting to explain observed correlations or looking for further compounds of potential interest to use in validation work. Here we introduce Linked Metabolites, a tool that identifies sets of reactions linking groups of compounds in the context of the KEGG pathway diagrams.
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