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Infantile hepatic hemangioendothelioma: an 8-month old infant successfully treated with a corticosteroid
Youssef Al-Tonbary1, Ashraf Fouda
1Mansoura University Children Hospital, Mansoura, Egypt. ytonbary@gmail.com
Insights
Infantile hemangioendothelioma, a rare liver tumor, can cause serious symptoms in infants. This case highlights successful treatment with oral prednisolone, offering hope for similar pediatric cases.
Area of Science:
- Pediatric Oncology
- Hepatology
- Vascular Malformations
Background:
- Infantile hemangioendothelioma (IHE) is the most common infantile liver tumor.
- While typically benign, large or diffuse IHE can lead to significant morbidity.
Observation:
- An 8-month-old female infant presented with hepatomegaly and respiratory distress.
- Imaging confirmed a large hepatic infantile hemangioendothelioma.
Findings:
- The infant received a six-month course of oral prednisolone.
- Treatment resulted in complete resolution of symptoms and tumor burden.
Implications:
- Oral prednisolone is an effective treatment option for symptomatic infantile hemangioendothelioma.
- Early diagnosis and intervention can lead to favorable outcomes in pediatric liver tumors.
Abstract:
Infantile hemangioendothelioma is a rare benign vascular tumor of the liver. We report a case of hepatic hemangioendothelioma in an 8- month-old female infant who presented with hepatomegaly and respiratory distress, which was successfully treated with oral prednisolone for six months.

