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Related Concept Videos

Resting Potential Decay01:15

Resting Potential Decay

The resting membrane potential of a neuron (-70mV) is sustained due to the selective ion permeability of the membrane. At the resting potential, the membrane is slightly permeable to ions like sodium (Na+) and chloride (Cl−) and highly permeable to potassium ions (K+). Differences in the ions' concentration inside the cell compared to the outside are maintained by membrane transport proteins like channels and pumps.
At rest, the K+ is the main ion that moves across the membrane through...
Resting Potential Decay01:15

Resting Potential Decay

The resting membrane potential of a neuron (-70mV) is sustained due to the selective ion permeability of the membrane. At the resting potential, the membrane is slightly permeable to ions like sodium (Na+) and chloride (Cl−) and highly permeable to potassium ions (K+). Differences in the ions' concentration inside the cell compared to the outside are maintained by membrane transport proteins like channels and pumps.
At rest, the K+ is the main ion that moves across the membrane through...
Resting Membrane Potential01:24

Resting Membrane Potential

The relative difference in electrical charge, or voltage, between the inside and the outside of a cell membrane, is called the membrane potential. It is generated by differences in permeability of the membrane to various ions and the concentrations of these ions across the membrane.
The Inside of a Neuron is More Negative
The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular fluid. The...
Resting Membrane Potential01:24

Resting Membrane Potential

The relative difference in electrical charge, or voltage, between the inside and the outside of a cell membrane, is called the membrane potential. It is generated by differences in permeability of the membrane to various ions and the concentrations of these ions across the membrane.
The Inside of a Neuron is More Negative
The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular fluid. The...
Atomic Nuclei: Nuclear Relaxation Processes01:23

Atomic Nuclei: Nuclear Relaxation Processes

In the absence of an external magnetic field, nuclear spin states are degenerate and randomly oriented. When a magnetic field is applied, the spins begin to precess and orient themselves along (lower energy) or against (higher energy) the direction of the field. At equilibrium, a slight excess population of spins exists in the lower energy state. Because the direction of the magnetic field is fixed as the z-axis,  the precessing magnetic moments are randomly oriented around the z-axis. This...
The Resting Membrane Potential01:21

The Resting Membrane Potential

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Related Experiment Video

Updated: Jun 16, 2026

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy
07:13

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy

Published on: May 27, 2020

Reading networks at rest.

Maki S Koyama1, Clare Kelly, Zarrar Shehzad

  • 1Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA. maki.koyama@nyumc.org

Cerebral Cortex (New York, N.Y. : 1991)
|February 9, 2010
PubMed
Summary
This summary is machine-generated.

Resting-state functional connectivity (RSFC) reveals brain networks for reading. Key areas like the posterior left middle temporal gyrus are crucial for word reading and may be implicated in dyslexia.

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Last Updated: Jun 16, 2026

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy
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Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Neuroimaging

Background:

  • Resting-state functional connectivity (RSFC) is a powerful neuroimaging technique for mapping brain networks.
  • Understanding the neural basis of reading is crucial for addressing reading disorders like dyslexia.

Purpose of the Study:

  • To investigate resting-state functional connectivity (RSFC) patterns associated with word reading networks.
  • To identify key brain regions involved in reading using functional magnetic resonance imaging (fMRI).

Main Methods:

  • Utilized fMRI to examine RSFC in 25 native English adult readers.
  • Selected regions of interest based on a meta-analysis of word reading studies.
  • Performed conjunction analyses to identify overlapping functional networks.

Main Results:

  • RSFC patterns mirrored task-based activity in reading networks.
  • The posterior left inferior frontal gyrus and posterior left middle temporal gyrus (post-LMTG) showed significant functional interaction.
  • Negative RSFC involved default mode network regions and areas related to controlled processing.

Conclusions:

  • Resting-state fMRI is a valuable tool for studying reading networks.
  • Findings highlight the post-LMTG's importance in reading and its potential role in dyslexia.
  • The study provides insights into the neural underpinnings of reading and reading disorders.