Related Experiment Video

Updated: Jun 16, 2026

Paradigms for Behavioral Assessment in Drosophila Model of Autism Spectrum Disorder
08:30

Paradigms for Behavioral Assessment in Drosophila Model of Autism Spectrum Disorder

Published on: September 6, 2024

Parental infertility and developmental coordination disorder in children

Jin Liang Zhu1, Carsten Obel, Olga Basso

  • 1The Danish Epidemiology Science Centre, Department of Epidemiology, School of Public Health, University of Aarhus, Bartholins Allé 2, 8000 Aarhus C, Denmark. zjl@soci.au.dk

Human Reproduction (Oxford, England)
|February 9, 2010
PubMed

Insights

Children conceived after a long time to pregnancy (TTP) showed a slightly higher risk of developmental coordination disorder (DCD). Infertility treatment was not significantly linked to DCD risk in children.

Area of Science:

  • Reproductive Medicine
  • Pediatric Neurology
  • Developmental Psychology

Background:

  • Previous studies suggest a slight delay in motor milestones for children born after infertility treatment.
  • This study investigates the risk of developmental coordination disorder (DCD) in children of infertile couples, with or without treatment.

Purpose of the Study:

  • To determine if children born to infertile couples, irrespective of treatment, have an increased risk of DCD.
  • To explore the association between time to pregnancy (TTP), infertility treatments, and DCD risk.

Main Methods:

  • Utilized data from the Danish National Birth Cohort (1996-2002) on 23,167 singletons.
  • Collected data on parental infertility, TTP, and infertility treatments during early pregnancy.
  • Assessed DCD risk in 7-year-old children using the Developmental Coordination Disorder Questionnaire completed by mothers.

Main Results:

  • Children conceived after a TTP >12 months had a modestly increased risk of DCD (OR 1.35, CI 1.03-1.77).
  • No significant association was found between infertility treatment and DCD risk (OR 1.19, CI 0.86-1.66).
  • Unplanned pregnancies and specific infertility treatments did not show an elevated DCD risk.

Conclusions:

  • Findings are generally reassuring regarding DCD risk in children of infertile couples.
  • A potential modest increase in DCD risk may be associated with low fecundity.
Abstract

More Related Videos

Concurrent Collection of Fetal Murine Brain and Serum to Assess Effects of Maternal Diet on Nutrition and Neurodevelopment in Neurofibromatosis Type 105:44

Concurrent Collection of Fetal Murine Brain and Serum to Assess Effects of Maternal Diet on Nutrition and Neurodevelopment in Neurofibromatosis Type 1

Published on: May 17, 2024

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers09:16

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers

Published on: March 14, 2018

Related Concept Videos

Oppositional Defiant Disorder01:30

Oppositional Defiant Disorder

A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Autism Spectrum Disorder01:19

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Intellectual Disability01:29

Intellectual Disability

Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
Conduct Disorder01:28

Conduct Disorder

Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...
Sex Linked Disorders01:43

Sex Linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.