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Two cases of severe invasive infections in children caused by Streptococcus pneumoniae serotype 14--case report

H Hupková1, I Urbancíková, K Bazárová

  • 1Institute of Microbiology, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovak Republic. helena.hupkova@fmed.uniba.sk

Folia Microbiologica
|February 9, 2010
PubMed

Insights

Severe pneumococcal infections in infants caused by serotype 14 Streptococcus pneumoniae can be fatal. Prompt, appropriate treatment of localized infections is crucial to prevent severe, generalized outcomes.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Microbiology

Background:

  • Streptococcus pneumoniae serotype 14 can cause severe invasive infections in infants.
  • Penicillin-nonsusceptible strains pose a treatment challenge.

Observation:

  • Two infant cases of severe pneumococcal infections (meningitis and pneumonia) caused by serotype 14 S. pneumoniae are detailed.
  • Both cases involved initial localized infections (otitis media, mastoiditis) that progressed to severe outcomes.

Findings:

  • One infant developed fatal penicillin-susceptible pneumococcal meningitis originating from acute otitis media.
  • An immunocompromised infant with recurrent otitis and chronic mastoiditis developed pneumococcal pneumonia.

Implications:

  • Highlights the critical need for timely and effective treatment of localized pneumococcal infections in infants.
  • Emphasizes the importance of considering appropriate antibiotics like amoxicillin for penicillin-susceptible strains to prevent invasive disease progression.

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