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Related Experiment Video

Updated: Jun 16, 2026

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging

Published on: March 13, 2019

A light-controlled molecular brake with complete ON-OFF rotation.

Meethale C Basheer¹, Yoshimi Oka, Manoj Mathews

¹Research Institute for Electronic Science, Hokkaido University, N20, W10, Sapporo, Hokkaido 001-0020, Japan.

Chemistry (Weinheim an Der Bergstrasse, Germany)

|February 9, 2010

Summary

Researchers developed a light-controlled molecular machine using azobenzenophanes. This machine acts as a molecular brake, controlling naphthalene rotation via light-induced azobenzene isomerization, enabling chiral switching.

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Area of Science:

Supramolecular Chemistry
Organic Chemistry
Photochemistry

Background:

Cyclic azobenzenophanes integrate photoisomerizable units with rotating moieties.
Controlling molecular motion with external stimuli is crucial for advanced materials.

Purpose of the Study:

To design and synthesize novel light-controlled molecular machines based on cyclic azobenzenophanes.
To demonstrate light-induced control over molecular rotation and chirality.

Main Methods:

Synthesis of dioxynaphthalene-azobenzene bridged cyclophanes.
NMR spectroscopy to study molecular rotation and isomerization.
Chiral High-Performance Liquid Chromatography (HPLC) for enantiomer resolution.

Main Results:

Achieved light-controlled switching of naphthalene rotation in azobenzenophanes.
Demonstrated a molecular brake effect where rotation is modulated by azobenzene photoisomerization (trans-OFF, cis-ON).
Established light-induced racemization of resolved enantiomers through E-Z isomerization.

Conclusions:

The synthesized cyclophanes function as effective light-controlled molecular machines.
The molecular brake mechanism offers precise control over molecular motion and chirality.
Photoinduced isomerization provides a viable method for dynamic control of molecular properties.