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Related Concept Videos

Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
Yellow Fever01:18

Yellow Fever

Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.

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[Features of hemorrhagic fever with renal syndrome with diabetes mellitus].

Terapevticheskii arkhiv·2020
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Borrelia miyamotoi infection leads to cross-reactive antibodies to the C6 peptide in mice and men.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2019
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[A comparative analysis of allele frequencies of rs1801133 and rs1801131 of MTHFR in patients with stroke and healthy people from the Moscow region].

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Serodiagnosis of Borrelia miyamotoi disease by measuring antibodies against GlpQ and variable major proteins.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2018
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[Complex assessment of the contribution of genetic factors to the risk of ischemic stroke].

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Related Experiment Video

Updated: Jun 16, 2026

Mosquito-Associated Virus Isolation from Field-Collected Mosquitoes
06:41

Mosquito-Associated Virus Isolation from Field-Collected Mosquitoes

Published on: August 31, 2022

[Prospects for treating mosquito-borne flavivirus encephalitides].

A E Platonov, L S Karan', Iu Ia Vengerov

    Terapevticheskii Arkhiv
    |February 10, 2010
    PubMed
    Summary

    Japanese encephalitis virus and West Nile virus cause severe neuroinvasive disease globally. New therapies require deeper understanding of flavivirus infection pathogenesis.

    Area of Science:

    • Virology
    • Epidemiology

    Context:

    • Japanese encephalitis virus (JEV) and West Nile virus (WNV) are significant mosquito-borne flaviviruses.
    • Both viruses share similar transmission cycles involving birds and Culex mosquitoes.
    • They are responsible for substantial global neuroinvasive disease burden.

    Purpose:

    • To review current knowledge on JEV and WNV.
    • To discuss clinical manifestations, pathogenesis, diagnosis, and treatment.
    • To highlight the need for novel etiotropic therapies.

    Summary:

    • JEV and WNV, flaviviruses transmitted by mosquitoes, cause severe neuroinvasive disease.
    • Review covers clinical aspects, pathogenesis, diagnosis, and treatment strategies.
    • Emphasis on developing targeted therapies based on pathogenesis insights.

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    Embryo Microinjection Techniques for Efficient Site-Specific Mutagenesis in Culex quinquefasciatus
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    Embryo Microinjection Techniques for Efficient Site-Specific Mutagenesis in Culex quinquefasciatus

    Published on: May 24, 2020

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    Last Updated: Jun 16, 2026

    Mosquito-Associated Virus Isolation from Field-Collected Mosquitoes
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    Published on: August 31, 2022

    A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
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    A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

    Published on: April 28, 2019

    Embryo Microinjection Techniques for Efficient Site-Specific Mutagenesis in Culex quinquefasciatus
    05:59

    Embryo Microinjection Techniques for Efficient Site-Specific Mutagenesis in Culex quinquefasciatus

    Published on: May 24, 2020

    Impact:

    • Informs clinicians and researchers about JEV and WNV.
    • Guides future research directions for flavivirus therapies.
    • Aims to improve patient outcomes for these arboviral infections.