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Related Experiment Video

Updated: Jun 16, 2026

Intrafemoral Injection of Human Hematopoietic Stem and Progenitor Cells into Immunocompromised Mice

Intrafemoral Injection of Human Hematopoietic Stem and Progenitor Cells into Immunocompromised Mice

Published on: December 8, 2023

Mankind's first natural stem cell transplant.

Jose N Tolosa¹, Dong-Hyuk Park, David J Eve

¹Department of Pediatrics, Division Neonatology, University of South Florida, College of Medicine, Tampa, FL 33612, USA.

Journal of Cellular and Molecular Medicine

|February 10, 2010

Summary

Delayed umbilical cord clamping offers significant benefits for newborns, including increased blood volume and prevention of anemia. This practice also facilitates the transfer of valuable stem cells from the placenta to the infant.

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Direct Induction of Human Neural Stem Cells from Peripheral Blood Hematopoietic Progenitor Cells

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Published on: December 8, 2023

Direct Induction of Human Neural Stem Cells from Peripheral Blood Hematopoietic Progenitor Cells

Direct Induction of Human Neural Stem Cells from Peripheral Blood Hematopoietic Progenitor Cells

Published on: January 28, 2015

Area of Science:

Neonatal Medicine
Pediatrics
Stem Cell Biology

Background:

The optimal timing for umbilical cord clamping remains a topic of debate in obstetrics and neonatology.
Historically, early clamping was prioritized for infant stabilization and resuscitation.
Emerging evidence supports delayed clamping for physiological benefits.

Purpose of the Study:

To review the advantages and disadvantages of delayed umbilical cord clamping.
To emphasize the role of delayed clamping in neonatal health and stem cell transfer.
To advocate for the encouragement of delayed cord clamping in routine births.

Main Methods:

This study is a review of existing clinical research and scientific literature.
Analysis of studies focusing on the physiological effects of delayed cord clamping.
Evaluation of the stem cell content in umbilical cord blood.

Main Results:

Delayed cord clamping increases infant blood volume and hemoglobin levels.
It is effective in preventing iron-deficiency anemia in newborns.
Umbilical cord blood is a rich source of various stem cells, including hematopoietic and mesenchymal progenitors.

Conclusions:

Delayed umbilical cord clamping offers substantial benefits for neonatal health.
It represents a crucial, natural transfer of stem cells from mother to infant.
Delayed clamping should be promoted in normal childbirth settings.