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Related Concept Videos

Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.

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Related Experiment Video

Updated: Jun 16, 2026

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
10:13

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Published on: February 14, 2014

[Risk factors for cognitive and functional impairment in the elderly].

Rubén de León-Arcila1, Feliciano Milián-Suazo, Nicolás Camacho-Calderón

  • 1Unidad de Medicina Familiar 2, Instituto Mexicano del Seguro Social, Querétaro, México. ruben.deleon@imss.gob.mx

Revista Medica Del Instituto Mexicano Del Seguro Social
|February 10, 2010
PubMed
Summary

Cognitive and functional impairments in older adults are linked to factors like stroke, diabetes mellitus type 2, and multidrug therapy. Addressing these can help prevent decline in the elderly.

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Area of Science:

  • Gerontology
  • Neuroscience
  • Public Health

Context:

  • Cognitive and functional impairments are significant concerns in the aging population.
  • Understanding associated risk factors is crucial for developing targeted interventions.
  • Previous research has explored various determinants, but a comprehensive analysis linking demographic, socioeconomic, health, and treatment factors is needed.

Purpose:

  • To investigate the association between cognitive and functional impairment and demographic, socioeconomic, chronic disease, and multidrug therapy factors in elderly patients.
  • To identify specific risk factors that can be targeted for prevention strategies.

Summary:

  • A cross-sectional study of 422 elderly individuals (≥60 years) utilized questionnaires and standardized assessments (Mini-Mental State Examination, Katz, Lawton and Bronfman instruments).
  • Logistic regression analysis revealed that stroke, female gender, and socioeconomic status were associated with cognitive impairment.
  • Diabetes mellitus type 2 was linked to impairment in daily activities, while female gender, visual impairment, and multidrug therapy were associated with difficulties in instrumental daily activities (all p < 0.05).

Impact:

  • Findings highlight specific modifiable and non-modifiable factors contributing to cognitive and functional decline in the elderly.
  • Identified associations can inform public health initiatives and clinical practice for preventive care in geriatric populations.
  • This research underscores the importance of a holistic approach, considering medical history, treatment regimens, and social determinants of health in elderly care.