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Live Dissection of Drosophila Embryos: Streamlined Methods for Screening Mutant Collections by Antibody Staining
Published on: December 29, 2009
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Duct tape for broken chromosomes
1Cell Cycle & Cancer Biology, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA. gjg@omrf.org
Cell
|February 10, 2010
Abstract:
A cell undergoing mitosis is presented with a potentially catastrophic situation when a DNA double-strand break creates a chromosome fragment that lacks connection to a centromere. Royou et al. (2010) now reveal that this cellular crisis is averted in fruit fly neuroblasts by thin chromatin tethers that hold on to the ends of the broken chromosomes.
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