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Related Experiment Video

Updated: Jun 16, 2026

Rapid Collection of Floral Fragrance Volatiles using a Headspace Volatile Collection Technique for GC-MS Thermal Desorption Sampling

Rapid Collection of Floral Fragrance Volatiles using a Headspace Volatile Collection Technique for GC-MS Thermal Desorption Sampling

Published on: December 10, 2019

Fragrance material review on phytol.

D McGinty¹, C S Letizia, A M Api

¹Research Institute for Fragrance Materials, Inc., Woodcliff Lake, NJ 07677, USA. dmcginty@RIFM.org

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association

|February 10, 2010

Summary

This review examines the safety of phytol, a fragrance ingredient, focusing on its toxicological and dermatologic effects. Phytol is generally considered safe for cosmetic use based on current data.

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Published on: June 2, 2023

Area of Science:

Toxicology
Dermatology
Cosmetic Science

Background:

Phytol is a naturally occurring terpene alcohol used as a fragrance ingredient in various consumer products.
Understanding the safety profile of fragrance ingredients is crucial for consumer protection and regulatory compliance.

Purpose of the Study:

To conduct a comprehensive toxicological and dermatologic review of phytol.
To evaluate the safety of phytol when used as a fragrance ingredient in cosmetic products.

Main Methods:

Literature review of existing toxicological and dermatological studies on phytol.
Analysis of safety data from regulatory bodies and scientific databases.

Main Results:

Phytol exhibits low acute toxicity.
Limited evidence suggests potential for skin sensitization in susceptible individuals at high concentrations.
No significant systemic toxicity concerns were identified.

Conclusions:

Phytol is considered safe for use as a fragrance ingredient at typical concentrations found in cosmetic products.
Further research on skin sensitization potential may be warranted for specific high-exposure scenarios.