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Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
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Th17 and Th1 T-cell responses in giant cell arteritis

Jiusheng Deng1, Brian R Younge, Richard A Olshen

  • 1Division of Immunology and Rheumatology, Stanford University School of Medicine, 269 W Campus Dr, Stanford, CA 94305, USA.

Circulation
|February 10, 2010
PubMed
Summary

Glucocorticoids suppress Th17 cells in giant cell arteritis (GCA) but not Th1 cells. Targeting persistent Th1 responses is crucial for resolving chronic vasculitis and monitoring T cell frequencies can assess GCA activity.

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