Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

Pulmonary Tuberculosis II

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

Tuberculosis

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...

Pulmonary Tuberculosis III

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:

Pulmonary Tuberculosis V

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...

Other Pulmonary Disorders

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Low Body Mass Index at Treatment Initiation and Rifampicin-Resistant Tuberculosis Treatment Outcomes: An Individual Participant Data Meta-Analysis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2022

Same author

COVID-19 Pandemic: Consensus guidelines for preferred practices in an aesthetic clinic.

Dermatologic therapy·2020

Same author

Discriminatory performance of adiponectin and leptin in the identification of impaired glucose tolerance: The Guangzhou Biobank Cohort Study - Cardiovascular Disease Subcohort.

PloS one·2018

Same author

Molecular Targets Related Drug Resistance Mechanisms in MDR-, XDR-, and TDR-<i>Mycobacterium tuberculosis</i> Strains.

Frontiers in cellular and infection microbiology·2018

Same author

Drug-resistant tuberculosis: An update on disease burden, diagnosis and treatment.

Respirology (Carlton, Vic.)·2018

Same author

Epidemiological, clinical and mechanistic perspectives of tuberculosis in older people.

Respirology (Carlton, Vic.)·2018

Search research articles

Related Experiment Video

Updated: Jun 16, 2026

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

Published on: October 5, 2015

Passive smoking and tuberculosis.

Chi C Leung¹, Tai H Lam, Kin S Ho

¹Department of Health, Hong Kong. cc_leung@dh.gov.hk

Archives of Internal Medicine

|February 10, 2010

Summary

Secondhand tobacco smoke exposure in the household increases the risk of developing tuberculosis (TB). This passive smoking increases the risk for active and culture-confirmed TB, highlighting the need for tobacco control.

More Related Videos

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

Published on: January 10, 2015

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis

Published on: August 16, 2021

Related Experiment Videos

Last Updated: Jun 16, 2026

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

Published on: October 5, 2015

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

Published on: January 10, 2015

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis

Published on: August 16, 2021

Area of Science:

Public Health
Epidemiology
Respiratory Medicine

Background:

Active smoking is a known risk factor for tuberculosis (TB).
The impact of secondhand tobacco smoke (SHS) exposure on TB development remains unclear.

Purpose of the Study:

To investigate the association between household passive smoking and the risk of developing TB in elderly never-smoking women.

Main Methods:

A prospective cohort study of 15,486 elderly never-smoking women in Hong Kong.
Follow-up via TB and death registries from 2000 to 2008.
Statistical analysis adjusted for confounding factors.

Main Results:

Passive SHS exposure was linked to obstructive lung disease and diabetes at baseline.
Passive smoking independently increased the risk of active TB (HR 1.49) and culture-confirmed TB (HR 1.70).
Passive smoking accounted for 13.7% of active TB and 18.5% of culture-positive TB in the cohort.

Conclusions:

Household passive smoking is a significant risk factor for TB development.
Tobacco control measures should be integrated into national TB programs.