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Related Experiment Video

Updated: Jun 16, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
10:28

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Biphasic calcium phosphate in periapical surgery.

Chinni Suneelkumar, Krithika Datta, Manali R Srinivasan

    Journal of Conservative Dentistry : JCD
    |February 10, 2010
    PubMed
    Summary

    Biphasic calcium phosphate, a blend of hydroxyapatite and beta-tricalcium phosphate, shows promise as a biocompatible bone substitute. Its osteoconductive properties make it suitable for clinical applications in periapical surgery.

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    Area of Science:

    • Biomaterials Science
    • Orthopedic Surgery
    • Dental Surgery

    Background:

    • Calcium phosphate ceramics, including hydroxyapatite and beta-tricalcium phosphate (beta-TCP), share mineral compositions similar to bone.
    • These materials exhibit excellent biocompatibility, making them suitable for bone regeneration applications.
    • Biphasic calcium phosphate (BCP) is a composite biomaterial comprising hydroxyapatite and beta-TCP in defined ratios.

    Observation:

    • BCP demonstrates osteoconductive potential, facilitating new bone formation.
    • The study focuses on the clinical application of BCP in periapical surgery.

    Findings:

    • Biphasic calcium phosphate serves as an effective bone substitute in periapical surgical procedures.
    • Clinical outcomes support the use of BCP for bone regeneration in this context.
    Keywords:
    Biphasic calcium phosphatebone substitutehydroxyapatiteosteoconductiveperiapical surgeryβ-tricalcium phosphate

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    Last Updated: Jun 16, 2026

    Biological Compatibility Profile on Biomaterials for Bone Regeneration
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    Implications:

    • BCP offers a viable alternative to traditional bone grafting materials in periapical surgery.
    • This highlights the potential of BCP in reconstructive dentistry and oral surgery.
    • Further research can explore long-term efficacy and broader applications of BCP in bone defect management.