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Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
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Published on: December 18, 2012

Recurrent hemolytic uremic syndrome.

G Lakshminarayana, R Rajesh, A Jojo

    Indian Journal of Nephrology
    |February 10, 2010
    PubMed
    Summary
    This summary is machine-generated.

    Recurrent hemolytic uremic syndrome (HUS) in adults, specifically diarrhea-negative (D-) HUS, is rare. This case highlights D-HUS in an adult female with hypocomplementemia, a condition affecting complement levels.

    Keywords:
    Hypocomplementemiahemolytic uremic syndromerecurrent acute renal failure

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    Area of Science:

    • Nephrology
    • Hematology
    • Immunology

    Background:

    • Hemolytic uremic syndrome (HUS) is a rare cause of acute kidney injury.
    • Diarrhea-associated (D+) HUS is common in children, while diarrhea-negative (D-) HUS involves diverse disorders.
    • D-HUS in adults is uncommon and presents diagnostic challenges.

    Observation:

    • This report details a rare instance of recurrent D-HUS in an adult female.
    • The patient presented with hypocomplementemia, indicating abnormal complement system activity.
    • The recurrent nature of D-HUS in this adult patient is noteworthy.

    Findings:

    • The case underscores the heterogeneity of D-HUS causes beyond typical pediatric presentations.
    • Hypocomplementemia may be a significant factor or indicator in adult D-HUS.
    • Recurrent D-HUS episodes in adults warrant thorough investigation into underlying pathologies.

    Implications:

    • This case expands the understanding of D-HUS presentation and potential etiologies in adults.
    • It suggests that hypocomplementemia should be considered in the workup of adult D-HUS.
    • Further research into non-diarrheal HUS in adults is crucial for improved diagnosis and management.