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Updated: Jun 16, 2026

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Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles
Published on: January 7, 2019
Recovery of nanoparticles made easy
Olesya Myakonkaya1, Clément Guibert, Julian Eastoe
1School of Chemistry, University of Bristol, Bristol BS8 1TS, United Kingdom.
Langmuir : the ACS Journal of Surfaces and Colloids
|February 11, 2010
Summary
Researchers developed a new method for nanoparticle recovery and reuse. This technique uses a special fluid with a liquid-liquid phase transition to control nanoparticle stability and enable separation.
Area of Science:
- Materials Science
- Colloid and Surface Chemistry
- Nanotechnology
Background:
- Nanoparticle (NP) stability and recovery are crucial for their sustainable use in various applications.
- Conventional methods for NP separation often involve harsh conditions or irreversible aggregation.
- Developing facile and reversible methods for NP recovery remains a significant challenge in nanotechnology.
Purpose of the Study:
- To demonstrate a novel approach for reversible control over nanoparticle stability.
- To enable facile recovery and subsequent reuse of inorganic nanoparticles.
- To introduce a new separation mechanism for nanostructures using colloidal fluids.
Main Methods:
- Utilizing a background-supporting colloidal fluid that exhibits a liquid-liquid critical-type phase transition.
- Suspending inorganic nanoparticles within this specialized colloidal fluid.
- Controlling nanoparticle separation and recovery by manipulating the temperature relative to the critical point T(c).
Main Results:
- Achieved reversible control over nanoparticle stability for the first time.
- Demonstrated facile recovery of inorganic nanoparticles.
- Successfully separated nanoparticles by leveraging the phase transition of the supporting colloidal fluid, avoiding traditional molecular solvents.
Conclusions:
- The novel approach offers a promising strategy for the sustainable and cost-effective reuse of inorganic nanoparticles.
- This method provides a new paradigm for nanoparticle separation and recovery, distinct from conventional techniques.
- The use of fluids with tunable phase transitions opens new avenues for advanced nanomaterial processing and applications.

