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Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...

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Related Experiment Video

Updated: Jun 16, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
08:57

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Malignant synovioma.

O Kogstad1

  • 1Dept. of Orthopedic Surgery, Telemark Central Hospital, Skien, Norway.

Scandinavian Journal of Rheumatology
|February 11, 2010
PubMed
Summary
This summary is machine-generated.

Malignant synoviomas can mimic arthritis, making early diagnosis by rheumatologists crucial. This review details two cases, highlighting clinical, histological, and imaging features, alongside treatment and prognosis for this rare tumor.

Related Experiment Videos

Last Updated: Jun 16, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
08:57

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Area of Science:

  • Oncology
  • Rheumatology
  • Pathology

Background:

  • Malignant synoviomas are rare soft tissue tumors.
  • Clinical presentation can mimic localized arthritis.
  • Early diagnosis is often challenging, requiring multidisciplinary input.

Purpose of the Study:

  • To describe the clinical, histological, and roentgenological features of malignant synoviomas.
  • To review the treatment and prognosis of this condition.
  • To emphasize the role of rheumatologists in early diagnosis.

Main Methods:

  • Case report analysis of two patients with malignant synovioma.
  • Review of relevant literature on synovioma diagnosis, treatment, and prognosis.
  • Description of clinical, histological, and imaging findings.

Main Results:

  • Malignant synoviomas present with variable clinical courses, ranging from rapid to prolonged.
  • Distinctive histological and roentgenological features aid in diagnosis.
  • Early recognition by rheumatologists can significantly impact patient outcomes.

Conclusions:

  • Rheumatologists play a key role in the early detection of malignant synoviomas.
  • Comprehensive evaluation including clinical, histological, and imaging data is essential.
  • Timely diagnosis and treatment are critical for improving prognosis in malignant synovioma.