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Related Experiment Video

Updated: Jun 16, 2026

Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients

Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients

Published on: June 11, 2011

[Infection due to Rhodococcus equi in HIV infected patients: four cases].

J Perez-Silvestre¹, V Abril López de Medrano, E Ortega González

¹Unidad de Enfermedades Infecciosas, Consorcio Hospital General Universitario, Valencia, España. jopesilver@hotmail.com

Revista Clinica Espanola

|February 11, 2010

Summary

Rhodococcus equi (R. equi) infection is increasingly seen in immunocompromised patients. This rare bacterial infection predominantly affects HIV-positive individuals, often causing severe cavitary pneumonia.

Related Experiment Videos

Last Updated: Jun 16, 2026

Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients

Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients

Published on: June 11, 2011

Area of Science:

Infectious Diseases
Microbiology
Pulmonology

Context:

Rising incidence of Rhodococcus equi infections observed alongside increased prevalence of immunosuppressed patient populations.
Rhodococcus equi infections are increasingly recognized as opportunistic infections in vulnerable individuals.

Purpose:

To characterize the clinical and epidemiological features of Rhodococcus equi infections within a single hospital setting.
To provide insights into the presentation and risk factors associated with R. equi infections.

Summary:

A retrospective study identified four cases of Rhodococcus equi infection between 1999 and 2007.
All patients were male, diagnosed with human immunodeficiency virus (HIV), and presented with severe immunosuppression (mean CD4+ count of 83 cells/microl).
Consistent findings included respiratory symptoms, cavitary pulmonary lesions, and positive blood and respiratory secretion cultures for R. equi.

Impact:

Highlights Rhodococcus equi as a significant pathogen in severely immunocompromised, particularly HIV-infected, individuals.
Emphasizes the typical presentation of cavitary pneumonia in R. equi infections.
Contributes to understanding the clinical spectrum of this rare but serious infection.