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Updated: Jun 16, 2026

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
Published on: September 22, 2020
[Incidence of lower extremity amputations in Area 3 of Madrid. Retrospective study during the period 2001-2006]
J A Rubio1, C Salido, A Albarracín
1Servicio de Endocrinología y Nutrición, Consulta de pie diabético, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España. jrubio.hupa@salud.madrid.org
Objective:
To quantify the Lower Extremity Amputations (LEA) incidence in population with and without diabetes mellitus (DM).
Material And Methods:
Retrospective cohort study of all the LEA carried out during 2001-2006 in area 3 of Madrid, from the codification of the reports of discharge reports.
Results:
310 LEA were carried out. The age-ajusted LEA incidence for any reason was 19,2/10(5) inhabitants per year (27,2 y 11,2 for men and women respectively). 261 were not-traumatic and non-tumoural (NTT) LEA, 76% were associated with DM and the incidence was 191/10(5) people with DM per year (95% confidence interval [CI(95)] 122-299) and 4,4/10(5) for people without DM per year (CI(95) 7-23), with a risk ratio of 44 (CI(95) 23-73).
Conclusions:
The LEA rates in population with o without diabetes are higher than the previously communicated in Madrid. It would appear convenient to design strategies to reduce the LEA rates.
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