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Related Experiment Video

Updated: Jun 16, 2026

Protocol for Plasmodium falciparum Infections in Mosquitoes and Infection Phenotype Determination

Protocol for Plasmodium falciparum Infections in Mosquitoes and Infection Phenotype Determination

Published on: July 4, 2007

[Malaria prophylaxis in the traveler].

J A Capdevila¹, R Icart

¹Servicio de Medicina Interna, Hospital de Mataró, Barcelona, España. jcapdevila@csdm.cat

Revista Clinica Espanola

|February 11, 2010

Summary

This summary is machine-generated.

Malaria is a preventable disease affecting millions of travelers annually. Chemoprophylaxis with appropriate antimalarial drugs is crucial for preventing severe illness, especially from P. falciparum.

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Area of Science:

Tropical medicine
Infectious disease epidemiology

Context:

Malaria is a significant global health concern, particularly in tropical and subtropical regions.
Approximately 125 million international tourists visit malaria-endemic areas annually, with an estimated 30,000 contracting the disease.
Prevention strategies include vector control and chemoprophylaxis to mitigate malaria risk in travelers.

Purpose:

To outline the principles of malaria prevention for international travelers.
To emphasize the importance of chemoprophylaxis in reducing severe malaria, particularly that caused by Plasmodium falciparum.
To guide the selection of appropriate antimalarial drugs based on drug resistance patterns and individual patient factors.

Summary:

Malaria prevention involves avoiding mosquito bites and taking antimalarial medications (chemoprophylaxis) before, during, and after travel.
The choice of chemoprophylactic drug depends on Plasmodium falciparum resistance profiles in the destination area.
Recommended drugs for areas with chloroquine resistance include Atovaquone/proguanil, Doxycycline, and Mefloquine, as advised by CDC and WHO.

Impact:

Informed travelers can significantly reduce their risk of contracting malaria.
Effective chemoprophylaxis can prevent severe malaria, reducing morbidity and mortality.
Adherence to drug recommendations ensures optimal protection against drug-resistant malaria strains.