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Related Concept Videos

Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...

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Substantiating Appropriate Motion Capture Techniques for the Assessment of Nordic Walking Gait and Posture in Older Adults
09:37

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Mobility in older adults: a comprehensive framework.

Sandra C Webber1, Michelle M Porter, Verena H Menec

  • 1Health, Leisure and Human Performance Research Institute, Faculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, MB, Canada R3T 2N2. swebber@cc.umanitoba.ca

The Gerontologist
|February 11, 2010
PubMed
Summary
This summary is machine-generated.

Mobility is crucial for active aging in older adults. This study introduces a new framework highlighting cognitive, psychosocial, physical, environmental, and financial factors influencing mobility across diverse environments.

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Last Updated: Jun 16, 2026

Substantiating Appropriate Motion Capture Techniques for the Assessment of Nordic Walking Gait and Posture in Older Adults
09:37

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Published on: October 6, 2016

Area of Science:

  • Gerontology
  • Public Health
  • Sociology

Background:

  • Mobility is vital for active aging, health, and quality of life in older adults.
  • Existing research on mobility is often discipline-specific and lacks a comprehensive view.
  • Understanding mobility's complexity is essential for promoting independence in aging populations.

Purpose of the Study:

  • To present a new theoretical framework for understanding mobility in older adults.
  • To raise awareness of the multifaceted factors influencing mobility.
  • To stimulate interdisciplinary research on mobility and aging.

Main Methods:

  • Defined mobility as self-movement within community environments, from home to broader regions.
  • Proposed a framework categorizing determinants of mobility into five key areas: cognitive, psychosocial, physical, environmental, and financial.
  • Identified gender, culture, and biography as critical cross-cutting influences on mobility.

Main Results:

  • Demonstrated increasing complexity of mobility determinants as the environment expands from home to community.
  • Illustrated how mobility impairments can restrict access to various life spaces.
  • Highlighted associations between different determinants influencing mobility.

Conclusions:

  • Advocates for interdisciplinary research to comprehensively address mobility concerns in older adults.
  • Suggests a need for more inclusive and integrated approaches to studying mobility.
  • Emphasizes developing complex strategies to overcome mobility challenges and support active aging.