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A Method for Murine Islet Isolation and Subcapsular Kidney Transplantation
Published on: April 13, 2011
Mesenchymal stem-cell immunosuppressive capabilities: therapeutic implications in islet transplantation
Yunchuan Ding1, Andrew Bushell, Kathryn J Wood
1Transplantation Research Immunology Group, Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom. yunchuan.ding@nds.ox.ac.uk
None:
Mesenchymal stem cells (MSCs) are known to be capable of suppressing immune responses and offer therapeutic potential for achieving transplantation tolerance. This review will discuss the impacts of MSCs on transplant immunity and focus on the potential role of MSCs in protecting islet grafts from both rejection and autoimmune attack.
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