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Repeat adverse events long after percutaneous coronary revascularization in diabetics

E Cavallero1, G Biondi-Zoccai, A Mazzanti

  • 1Division of Cardiology, University of Turin, Turin, Italy.

Minerva Cardioangiologica
|February 11, 2010
PubMed

Insights

Diabetics with coronary artery disease frequently experience recurrent adverse cardiac events after percutaneous coronary intervention (PCI). Repeat PCI is often a safe and successful management strategy for these patients.

Area of Science:

  • Cardiology
  • Diabetology
  • Interventional Cardiology

Background:

  • Diabetics with coronary artery disease (CAD) have a high risk of adverse events post-coronary revascularization.
  • Recurrence rates after initial revascularization in diabetic patients remain under-evaluated.

Purpose of the Study:

  • To assess the long-term rates of recurrent adverse events in diabetic patients undergoing percutaneous coronary intervention (PCI).
  • To evaluate the safety and efficacy of repeat PCI in managing recurrent events in this population.

Main Methods:

  • Retrospective analysis of 429 type-2 diabetic patients treated with PCI between July 2002 and December 2005.
  • Data collection included baseline characteristics and long-term outcomes.
  • Key endpoints: major adverse cardiac events (MACE), repeat target vessel revascularization (TVR-PCI), non-TVR PCI, and stent thrombosis.

Main Results:

  • A total of 429 diabetic patients were included; 54% received drug-eluting stents.
  • At a median follow-up of 38 months, MACE occurred in 38.9% of patients.
  • Among 129 patients needing repeat revascularization, 21.7% required a second TVR-PCI, 5.4% a third, and 1.5% a fourth.

Conclusions:

  • Diabetic patients undergoing PCI face frequent adverse events, including a significant rate of repeat revascularization.
  • Repeat PCI appears to be a safe and effective strategy for managing recurrent events in this high-risk group.
Abstract

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